In vitro anti-HIV activity of crude extracts from Tinospora cordifolia
نویسندگان
چکیده
Background Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/ AIDS patients. However, emergence of HIV drug resistance, side effects and the necessity for long-term antiHIV treatment are the main reasons for failure of antiHIV therapy. Therefore, it is essential to isolate novel anti-HIV therapeutics from natural resources. The aim of the present study was to evaluate the invitro antiHIV activity of T. cordifolia plant extracts.
منابع مشابه
Evaluation of Ocimum sanctum and Tinospora cordifolia as Probable HIV - Protease Inhibitors
Ethanol extracts of Ocimum sanctum Linn. and Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIV-protease in proteolytic activity. Extracts of O. sanctum and T. cordifolia showed potent inhibitory activity...
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